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Antigenic Specificity | Carcinoembryonic Antigen (CEA)/CD66 |
Clone | [C66/1983R] |
Host Species | Rabbit |
Reactive Species | human. |
Isotype | IgG |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivit |
Immunogen | Immunogen: Human colon carcinoma extract. Cellular Localization: Cytoplasmic and luminal surface |
Other Names | [Carcinoembryonic Antigen-related Cell Adhesion Molecule 5; CEACAM5; CD66; Biliary Glycoprotein (BGP-1)], [CD66; CEACAM1; CEACAM5] |
Gene, Accession # | [CEA], Gene ID: 1048, NCBI: NP_001278413.1, UniProt: P06731 |
Catalog # | MBS439847 |
Price | $190, $340, $340 |
Order / More Info | Carcinoembryonic Antigen (CEA)/CD66 Antibody from MYBIOSOURCE INC. |
Product Specific References | Shi ZR, et. al. Journal of Histochemistry and Cytochemistry, 1994, 42(9):1215-9. Robbins PF, et. al. International Journal of Cancer, 1993, 53(6):892-7. Muraro R, et. al. Cancer Research, 1985, 45:5769-80. Siler K, et. al. Biotechnology Therapeutics, 1993, 4(3-4):163-81. |