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Antigenic Specificity | TWNK - middle region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against PEO1. It was validated on Western Blot using a cell lysate as a positive control.Target Description: This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple tra |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PEO1 |
Other Names | [twinkle protein, mitochondrial isoform A; Twinkle protein, mitochondrial; twinkle protein, mitochondrial; twinkle mtDNA helicase; Progressive external ophthalmoplegia 1 protein; T7 gp4-like protein with intramitochondrial nucleoid localization; T7-like mitochondrial DNA helicase] |
Gene, Accession # | [TWNK], Gene ID: 56652, NCBI: NP_068602, UniProt: Q96RR1 |
Catalog # | MBS3203156 |
Price | $365 |
Order / More Info | TWNK - middle region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |