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Antigenic Specificity | HLA-DR/HLA-DRA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, Flow Cytometry (FC/FACS), Direct ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for HLA-DR/HLA-DRA detection. Tested with WB, IHC-P, FCM, Direct ELISA in Human; Mouse; Rat.Background: HLA class II histocompatibility antigen, DR alpha chain is a protein that in humans is encoded by the HLA-DRA gene. It is mapped to 6p21.32. HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha |
Immunogen | Immunogen: E. coli-derived human HLA-DR/HLA-DRA recombinant protein (Position: I26-L254). |
Other Names | [HLA class II histocompatibility antigen, DR alpha chain; MHC class II antigen DRA; HLA-DRA; HLA-DRA1] |
Gene, Accession # | [HLA-DR], Gene ID: 3122, UniProt: P01903 |
Catalog # | MBS1752853 |
Price | $315 |
Order / More Info | HLA-DR/HLA-DRA Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Tjernlund U, Scheynius A, Johansson C, et al. (1989). T-cell response to purified protein derivative after removal of Langerhans' cells from epidermal cell suspensions containing keratinocytes expressing class II transplantation antigens. Scand. J. Immunol. 28 (6): 667-73. 2. Chelladurai, M., Honn, K. V., Walz, D. A. HLA-DR is a procoagulant. Biochem. Biophys. Res. Commun. 178: 467-473, 1991. 3. Das, H. K., Lawrance, S. K., Weissman, S. M. Structure and nucleotide sequence of the heavy chain gene of HLA-DR. Proc. Nat. Acad. Sci. 80: 3543-3547, 1983. |