HLA-DR/HLA-DRA Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHLA-DR/HLA-DRA
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mg
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC) Paraffin, Flow Cytometry (FC/FACS), Direct ELISA (EIA)
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DescriptionSpecificity: No cross reactivity with other proteins. Description: Rabbit IgG polyclonal antibody for HLA-DR/HLA-DRA detection. Tested with WB, IHC-P, FCM, Direct ELISA in Human; Mouse; Rat.Background: HLA class II histocompatibility antigen, DR alpha chain is a protein that in humans is encoded by the HLA-DRA gene. It is mapped to 6p21.32. HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha
ImmunogenImmunogen: E. coli-derived human HLA-DR/HLA-DRA recombinant protein (Position: I26-L254).
Other Names[HLA class II histocompatibility antigen, DR alpha chain; MHC class II antigen DRA; HLA-DRA; HLA-DRA1]
Gene, Accession #[HLA-DR], Gene ID: 3122, UniProt: P01903
Catalog #MBS1752853
Price$315
Order / More InfoHLA-DR/HLA-DRA Antibody from MYBIOSOURCE INC.
Product Specific References1. Tjernlund U, Scheynius A, Johansson C, et al. (1989). T-cell response to purified protein derivative after removal of Langerhans' cells from epidermal cell suspensions containing keratinocytes expressing class II transplantation antigens. Scand. J. Immunol. 28 (6): 667-73. 2. Chelladurai, M., Honn, K. V., Walz, D. A. HLA-DR is a procoagulant. Biochem. Biophys. Res. Commun. 178: 467-473, 1991. 3. Das, H. K., Lawrance, S. K., Weissman, S. M. Structure and nucleotide sequence of the heavy chain gene of HLA-DR. Proc. Nat. Acad. Sci. 80: 3543-3547, 1983.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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