Nephrin Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNephrin
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionNephrin Antibody: Nephrin is strongly expressed in renal glomeruli and is a member of the immunoglobulin family of cell adhesion molecules. Mutations in the Nephrin gene result in congenital nephrotic syndrome, an autosomal-recessive disorder characterized by massive proteinuria in utero and nephrosis at birth. Renal glomeruli allow normal kidneys to filter plasma so that it is very pure. Nephrin is expressed in the podocyte slit-diaphragm of the renal glomeruli in a manner that suggests that Nephrin molecules homodimerize in an anti-parallel fashion similar to cadherin interactions in adherens junctions. Thus, Nephrin may constitute the entire extracellular structure of the slit-diaphragm.
ImmunogenImmunogen: Nephrin antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human Nephrin. Buffer: Nephrin Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[Nephrin; CNF; NPHN; nephrin; Nephrin; Renal glomerulus-specific cell adhesion receptor; nephrosis 1, congenital, Finnish type (nephrin)], [NPHS1; NPHS1; CNF; NPHN; nephrin; NPHN]
Gene, Accession #[NPHS1], Gene ID: 4868, NCBI: NP_004637, UniProt: O60500
Catalog #MBS151503
Price$375
Order / More InfoNephrin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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