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Antigenic Specificity | Human PAI-1 |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | chimpanzee (expected from sequence), dog (expected from sequence) |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | IgG concentration 0.5 mg/ml |
Applications | ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Goat anti human PAI-1 antibody recognizes human Plasminogen activator inhibitor 1 (PAI-1), also known as Serpin E1. PAI-1 is a 402 amino acid }45kDa serine protease inhibitor epitope within the internal region of human Serpin E1. PAI-1 (Serpin E1) is a 45kD serine protease inhibitor and the principle inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA) PAI-1 is present in plasma, platelets and endothelial cells, is expressed at increased levels in various disease states (Kruithof et al. 1988), and has been linked to an increased occurrence of thrombosis in obesity and coronary artery disease (Oseroff et al. 1989). Defects in PAI-1 are characterized by abnormal bleeding (Takahashi et al. 1996). Goat anti human PAI-1 antib |
Immunogen | Histology Positive Control Tissue: Human Placenta Buffer Solution: TRIS buffered saline Antiserum Preparation: Antisera to human PAI-1 were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography. Target Species: Human |
Other Names | [plasminogen activator inhibitor 1; Plasminogen activator inhibitor 1; plasminogen activator inhibitor 1; endothelial plasminogen activator inhibitor; serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; serpin E1; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Endothelial plasminogen activator inhibitor; Serpin E1], [SERPINE1; SERPINE1; PAI; PAI1; PAI-1; PLANH1; PAI1; PLANH1; PAI; PAI-1] |
Gene, Accession # | [PAI-1], Gene ID: 5054, NCBI: NP_000593.1, UniProt: P05121 |
Catalog # | MBS221393 |
Price | $550 |
Order / More Info | Human PAI-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |