PLCD4 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPLCD4
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionHydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca(2+) from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca(2+) mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.
ImmunogenImmunogen: Recombinant human 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 protein (N-290AA)
Other Names[1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase delta-4; hPLCD4; Phosphoinositide phospholipase C-delta-4; Phospholipase C-delta-4; PLC-delta-4; PLCD4]
Gene, Accession #[PLCD4], Gene ID: 84812, NCBI: NP_116115.1, UniProt: Q9BRC7
Catalog #MBS7044388
Price$120, $160
Order / More InfoPLCD4 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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