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Antigenic Specificity | PI 3 Kinase p85 alpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: PI 3 Kinase p85 alpha Antibody detects endogenous levels of total PI 3 Kinase p85 alpha. Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. |
Immunogen | Immunogen: A synthesized peptide derived from human PI 3 Kinase p85 alpha |
Other Names | [GRB1; P85A; PI3-kinase p85-alpha; PI3K p85-alpha; ptdIns-3-kinase p85-alpha] |
Gene, Accession # | [PI3K], Gene ID: 5295, NCBI: NP_001229395.1, UniProt: P27986 |
Catalog # | MBS4750132 |
Price | $335 |
Order / More Info | PI 3 Kinase p85 alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |