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Antigenic Specificity | Splicing factor 1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Splicing factor 1 antibody detects endogenous levels of total Splicing factor 1. Function: Necessary for the ATP-dependent first step of spliceosome assembly. Binds to the intron branch point sequence (BPS) 5'-UACUAAC-3' of the pre-mRNA. May act as transcription repressor.Subunit Structure: Binds U2AF2. Interacts with U1 snRNA. Binds EWSR1, FUS and TAF15. Interacts with RBM17.Post-translational Modifications: Phosphorylation on Ser-20 interferes with U2AF2 binding and spliceosome assembly. Isoform 6 is phosphorylated on Ser-463.Similarity: Belongs to the BBP/SF1 family. |
Immunogen | Immunogen: A synthesized peptide derived from human Splicing factor 1 Subcellular Location: Nuclear Tissue Specificity: Detected in lung, ovary, adrenal gland, colon, kidney, muscle, pancreas, thyroid, placenta, brain, liver and heart. |
Other Names | [BBP; D11S636; Mammalian branch point binding protein mBBP; OTTHUMP00000069749; OTTHUMP00000069750; OTTHUMP00000069752; Splicing factor 1; Transcription factor ZFM1; ZFM1; Zinc finger gene in MEN1 locus; Zinc finger protein 162; ZNF162] |
Gene, Accession # | [SF1], Gene ID: 7536, NCBI: NP_001171501.1, UniProt: Q15637 |
Catalog # | MBS9602245 |
Price | $240, $280 |
Order / More Info | Splicing factor 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |