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Antigenic Specificity | MICA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1 mg/mL |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes the highly polymorphic major histocompatability complex class I chain-related protein A. The protein product is expressed on the cell surface, although unlike canonical class I molecules it does not seem to associate with beta-2-microglobulin. It is a ligand for the NKG2-D type II integral membrane protein receptor. The protein functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Variations in this gene have been associated with susceptibility to psoriasis 1 and psoriatic arthritis, and the shedding of MICA-related antibodies and ligands is involved in the progression from monoclonal gammopathy of undetermined significance to multiple myeloma. Alternative splicing o |
Immunogen | Immunogen: Recombinant protein of human MICA |
Other Names | [HLA class I antigen; FLJ36918; FLJ60820; MGC111087; MGC21250; MHC class I chain related gene A protein; MHC class I chain related protein A; MHC class I chain related protein A HLA B HLA C; MHC class I polypeptide related sequence A; MHC class I polypeptide-related sequence A; MHC class I related protein; MIC A; MIC-A; micA; MICA; OTTHUMP00000029088; OTTHUMP00000044528; OTTHUMP00000165170; OTTHUMP00000165172; PERB11.1; Stress inducible class I homolog] |
Gene, Accession # | [MICA], Gene ID: 100507436, NCBI: NP_000238.1, UniProt: Q29983 |
Catalog # | MBS2554147 |
Price | $150, $225, $360 |
Order / More Info | MICA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |