Ficolin-3, Human Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Ficolin-3, Human antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Ficolin-3, Human |
| Clone | 4H5 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Immunohistochemistry (IHC) Formalin, Immunoassay, Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The monoclonal antibody 4H5 recognizes human Ficolin-3, also known as H-ficolin. Ficolins are a family of pattern recognition molecules containing both a collagen-like domain and a fibrinogen-like domain that are capable of activating the complement system, through association with MASPs, on the surface of microorganisms. In human, three Ficolins are known: Ficolin-1 (M-ficolin), Ficolin-2 (L-ficolin), and Ficolin-3 (H-ficolin). Ficolin-1, is mainly expressed by monocytes, granulocytes and lung cells and is present locally in areas of inflammation. Ficolin-3 (also Hakata antigen, H-ficolin or ficolin H) is produced by the liver and by the lung. Ficolin-3 is associated with three types of MASPs and sMAP, this complex activates C4, C2 and C3 |
| Immunogen | n/a |
| Other Names | [ficolin-3 isoform 1; Ficolin-3; ficolin-3; ficolin 3; Collagen/fibrinogen domain-containing lectin 3 p35; Collagen/fibrinogen domain-containing protein 3; Hakata antigen], [FCN3; FCN3; FCNH; HAKA1; FCNH; HAKA1] |
| Gene, Accession # | Gene ID: 8547, NCBI: NP_003656.2, UniProt: O75636 |
| Catalog # | MBS584807 |
| Price | $665 |
| Order / More Info | Ficolin-3, Human Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Matsushita, M et al; Activation of the lectin complement pathway by ficolins. Int Immunopharmacol 2001, 1: 359. 2. Matsushita, M et al; Activation of the lectin complement pathway by H-ficolin (Hakata antigen). J of Immunol 2002, 168: 3502. 3. Matsushita, M et al; The role of ficolins in innate immunity. Immunobiol 2002, 205: 490. 4. Kuraya, M et al; Expression of H-ficolin/Hakata antigen, mannose-binding lectin-associated serine protease (MASP)-1 and MASP-3 by human glioma cell line T98G. Int Immunol 2003, 15: 109. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies