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Antigenic Specificity | MYOZAP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Multiple isoforms of MYOZAP are known to exist. MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein. It is strongly expressed in the heart and lung and is a novel component of intercalated disc. MYOZAP interacts with myosin phosphatase-RhoA interacting protein (MRIP) and acts as an activator of Rho-dependent SRF signaling. Knockdown study in zebrafish results in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A). Transcription of this gene occurs at an upstream promoter, with two different groups of alternatively spliced variants: Gup for GRINL1A upstream transcripts |
Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 18 amino acid peptide near the carboxy terminus of human MYOZAP. |
Other Names | [Myocardium-enriched zonula occludens-1e'' - c?Cinteracting protein, glutamate receptor ionotropic N-methyl D-aspartate-like 1A, GRINL1A, GCOM1, Gup, Gup1] |
Gene, Accession # | [MYOZAP], Gene ID: 100820829, NCBI: NP_001018110 |
Catalog # | MBS9410237 |
Price | $320 |
Order / More Info | MYOZAP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |