AXIN2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | AXIN2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: AXIN2 antibody is predicted to not cross-react with AXIN2. At least four isoforms of AXIN2 are known to exist; this antibody will recognize all four. Like the related protein AXIN1, AXIN2 is thought to play an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway. In mouse, AXIN2 organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and AXIN2, which leads to the degradation of beta-catenin, which is thought to be an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumor |
| Immunogen | Immunogen Type: Peptide Immunogen Description: Raised against a 20 amino acid peptide near the carboxy terminus of human AXIN2. |
| Other Names | [AXIL, AXI1, conductin] |
| Gene, Accession # | [AXIN2], Gene ID: 8313, NCBI: AAF22799 |
| Catalog # | MBS9410234 |
| Price | $320 |
| Order / More Info | AXIN2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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