LBP, Mouse Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | LBP, Mouse |
| Clone | M330-19 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), Immunoassay (IA), Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The monoclonal antibody M330-19 reacts highly specific with mouse natural and recombinant LBP. The antibody is a type I antibody blocking the LPS binding to LBP. LPS binding protein (LBP) is an approximately 60 kDa acute phase protein that is produced by hepatocytes. This protein strongly binds to LPS and has been shown to play an important role in the handling of LPS by the host. A number of functions of LBP have been reported. First, LBP transfers LPS to the LPS receptor CD14 on mononuclear phagocytes, leading to an 100-1,000-fold increased sensitivity of the cells to LPS. Furthermore, LBP can enhance the response of CD14 negative cells by acceleration of LPS binding to soluble CD14, a complex that stimulates these ce |
| Immunogen | n/a |
| Other Names | [Lipopolysaccharide-binding protein; Lipopolysaccharide-binding protein; lipopolysaccharide-binding protein; LPS-binding protein; BPI fold containing family D, member 2; lipopolysaccharide binding protein], [LBP; LBP; BPIFD2; LBP] |
| Gene, Accession # | [LBP], Gene ID: 3929, NCBI: P18428.3 |
| Catalog # | MBS584138 |
| Price | $520 |
| Order / More Info | LBP, Mouse Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1.Le Roy, D et al; Monoclonal antibodies to murine lipopolysaccharide (LPS)-binding protein (LBP) protect mice from lethal endotoxemia by blocking either the binding of LPS to LBP or the presentation of LPS/LBP complexes to CD14. J Immunol 1999, 162: 7454 2. Le Roy, D et al; Critical role of lipopolysaccharide-binding protein and CD14 in immune response against gram-negative bacteria. J Immunol 2001, 169: 2759 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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