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Antigenic Specificity | HLA-E |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.9 mg/mL |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total HLA-E protein. HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. |
Immunogen | Immunogen: Fusion protein of human HLA-E Immunogen Type: Peptide |
Other Names | [QA1; HLA-6.2] |
Gene, Accession # | [HLA-E], Gene ID: 3133, NCBI: NP_005507.3, UniProt: P13747 |
Catalog # | MBS9430720 |
Price | $255 |
Order / More Info | HLA-E Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |