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Antigenic Specificity | TNFSF13 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: TNFSF13 antibody detects endogenous levels of total TNFSF13. Description: BAFF, a member of the TNF superfamily of proteins, is a homotrimeric transmembrane protein, which is cleaved to produce a soluble cytokine (1). BAFF may also further oligomerize into 60-mer structures (1). BAFF is expressed by neutrophils, macrophages, dendritic cells, activated T cells, and epithelial cells (1, 2). BAFF plays a key role in B cell development, survival, and activation (1, 3, 4). BAFF binds to three distinct receptors, BAFF-R, TACI, and BCMA (1). These receptors are differentially expressed during B cell development and among B cell subsets (1, 2, 4). While BAFF-R and BCMA bind to the homotrimeric form of BAFF, TACI only binds to membrane |
Immunogen | Immunogen: A synthesized peptide derived from human TNFSF13 Subcellular Location: Secreted. Tissue Specificity: Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. |
Other Names | [A proliferation inducing ligand; A proliferation-inducing ligand; APRIL; CD256; TALL-2; TALL2; TNF related death ligand; TNF-and APOL-related leukocyte expressed ligand 2; TNF-related death ligand 1; TNF13_HUMAN; TNFSF13; TRDL-1; TRDL1; Tumor necrosis factor (ligand) superfamily, member 13; Tumor necrosis factor ligand superfamily member 13; Tumor necrosis factor like protein ZTNF2; Tumor necrosis factor related death ligand 1; UNQ383/PRO715; ZTNF2] |
Gene, Accession # | [TNFSF13], Gene ID: 8741, NCBI: NP_001185552.1, UniProt: O75888 |
Catalog # | MBS9607027 |
Price | $240, $280 |
Order / More Info | TNFSF13 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |