AHA1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | AHA1 |
| Clone | [4H9-D7] |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG1 Kappa |
| Format | APC-Cy7 conjugate |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~38 kDa, can run up to 45 kDa on SDS Page. It sees human Aha1, Mouse Aha1 and Mouse Aha2. Aha1 is a member of the HSP90 cochaperone family, and is thought to stimulate HSP90 ATPase activity by competing with p23 and other co-chaperones for HSP90 binding (1, 2). It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/HSP90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) (3). Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors (4). |
| Immunogen | Immunogen: Human Aha1, his tagged |
| Other Names | [Mouse Human AHA1 IgG1 Kappa; AHA1 : APC/Cy7; Aha 1; Ahsa1; p38; HSPC322; C14orf3; Activator of HSP90 ATPase; Activator of 90 kDa heat shock protein ATPase homolog 1] |
| Gene, Accession # | [AHA1], Gene ID: 10598, NCBI: NP_036243.1, UniProt: O95433 |
| Catalog # | MBS8002566 |
| Price | $495 |
| Order / More Info | AHA1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Hainzl O., Lapina M.C., Buchner J., Richter K. (2009) J Biol Chem. Epub. 2. Harst A., Lin H., Obermann W.M. (2005) Biochem J. 387 (pt.3): 789-796. 3. Lotz G.P., Brychzy A., Heinz S., Obermann W.M. (2008) J Cell Sci. 121(pt.5): 717-723. 4. Holmes J.L., Sharp S.Y., Hobbs S., Workman P. (2008) Cancer Res. 68(4): 1188-1197. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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