IRF8 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-IRF8 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | IRF8 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mg |
| Concentration | 1 mg/mL |
| Applications | ELISA (EIA), Western Blot (WB), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IRF8 Antibody: Interferons (IFN)s are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-alpha/beta genes. Unlike IRF3, IRF8 appears to act as a negative regulator of IFN-induced genes in most cases, but IRF8 mediates activation of NF-κB by the toll-like receptor 9 (TLR9) after stimulation by unmethylated CpG DNA in dendritic cells. Finally, it has been shown that IRF8 decreases bcl-2 expression and thus may play a role in chronic |
| Immunogen | Immunogen: IRF8 antibody was raised against a peptide corresponding to 16 amino acids near the carboxy terminus of human IRF8. Buffer: IRF8 Antibody is supplied in PBS containing 0.02% sodium azide. |
| Other Names | [IRF8; Interferon regulatory factor 3; IRF-3; interferon regulatory factor 3], [IRF8; IRF8; ICSBP; IRF-8; ICSBP1; IMD32A; IMD32B; H-ICSBP; ICSBP1; IRF-8; H-ICSBP; ICSBP] |
| Gene, Accession # | [IRF3], Gene ID: 3394, NCBI: NP_002154, UniProt: Q14653 |
| Catalog # | MBS150591 |
| Price | $375 |
| Order / More Info | IRF8 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies