Human ICAM3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman ICAM3
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman
IsotypeIgG
Formatunconjugated
Size0.06 mL, 0.12 mL, 0.2 mL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC) Paraffin
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DescriptionThe protein ICAM-3, also known as CD50, is a member of the intercellular adhesion molecule (ICAM) family consisting three members. It is a DC-SIGN ligand that is constitutively expressed on resting leukocytes, and is thus an important molecule for the first immune response. ICAM-3 comprises of five immunoglobulin-like domains, and binds LFA-1 through its two N-terminal domains. It functions not only as an adhesion molecule, but also as a potent signalling molecule. ICAM-3 binds to LFA-1 on antigen-presenting cells (APC) stabilizing the T cell-APC interaction, facilitating signaling through the CD3/TCR complex. However, recent evidence using cultured and transformed T cells suggests ICAM-3 may also function in signaling. It has been reported
ImmunogenImmunogen: Recombinant Human CD50/ICAM-3 protein Buffer: 0.2 mum filtered solution in PBS with 5% trehalose
Other Names[intercellular adhesion molecule 3 isoform 3; Intercellular adhesion molecule 3; intercellular adhesion molecule 3; intercellular adhesion molecule 3; CDw50; ICAM-R; CD_antigen: CD50]
Gene, Accession #[ICAM3 ], Gene ID: 3385
Catalog #MBS2543940
Price$215, $330, $500
Order / More InfoHuman ICAM3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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