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Antigenic Specificity | uPAR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.03 mg, 0.1 mg |
Concentration | 0.5 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: uPAR (Urokinase plasminogen activator receptor) is a 55 kDa glycoprotein I-anchored surface receptor specific for urokinase plasminogen activator (uPA). Upon binding to uPAR, uPA converts the surface bound, large serum beta-globulin, plasminogen to plasmin. Plasmin, which is also designated fibrinolysin, is a trypsin-like enzyme that acts on Arg-Lys bonds and induces pericellular proteolysis in fibrin and fibrinogen, and thereby contributes to the systematic activation of the coagulation cascade. uPA and uPAR are known to be overexpressed in mesenchymal and epithelial tumor cells and are required for tumor invasion and metastasis. |
Immunogen | Immunogen: Synthetic peptide surrounding amino acid 51 of rat uPAR |
Other Names | [Urokinase plasminogen activator receptor; PLAUR; uPAR; CD87; MO3; UPAR; URKR; Urokinase plasminogen activator surface receptor; U-PAR; uPAR; Monocyte activation antigen Mo3; CD_antigen; CD87], [Plaur; Plaur; Par; uPAR; Plaur3; uPAR-2; uPAR-3; U-PAR; uPAR] |
Gene, Accession # | [uPAR], Gene ID: 50692, NCBI: NP_059046.1, UniProt: P49616 |
Catalog # | MBS841353 |
Price | $150, $290 |
Order / More Info | uPAR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |