Human CD82 (C-TERMINAL) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman CD82 (C-TERMINAL)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formatunconjugated
Size0.1 mg
ConcentrationIgG concentration 1.0mg/ml
ApplicationsImmunohistology Paraffin*, Western Blot (WB)
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DescriptionThis item recognises the human CD82 antigen, also known as KAI1, SAR2 and TSPAN27, a multi-pass membrane protein of approximately 30kDa belonging to the tetraspanin (TM4SF) family. . . CD82 has been identified as a cancer metastasis suppressor protein, while ubiquitously expressed at moderate to high levels in many normal tissues, its expression is down regulated during tumour progression. Loss of CD82 and p53 is correlated with poor prognosis for patients with prostate and other forms of cancer. . . Research has demonstrated that CD82 interacts with CD234 (DARC). It has been hypothesized that tumour cells dislodged from the primary tumour and expressing CD82 interact with CD234 expressed on vascular cells, transmitting a senescent sign
ImmunogenImmunogen: A peptide corresponding to a 15 amino acid sequence from near the carboxy terminus of Human CD82. Histology Positive Control Tissue: Human colon tissue Buffer Solution: Phosphate buffered saline Antiserum Preparation: Antisera to Human CD82 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography. Target Species: Human
Other Names[CD82 antigen isoform 2; CD82 antigen; CD82 antigen; C33 antigen; inducible membrane protein R2; kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by and IA4)); metastasis suppressor Kangai-1; tetraspanin-27; tspan-27; CD82 molecule; C33 antigen; IA4; Inducible membrane protein R2; Metastasis suppressor Kangai-1; Suppressor of tumorigenicity 6 protein; Tetraspanin-27; Tspan-27; CD_antigen: CD82], [CD82; CD82; R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27; KAI1; SAR2; ST6; TSPAN27; Tspan-27]
Gene, Accession #[CD82], Gene ID: 3732, NCBI: NP_001020015.1, UniProt: P27701
Catalog #MBS224140
Price$375
Order / More InfoHuman CD82 (C-TERMINAL) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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