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Antigenic Specificity | ATP-Citrate Lyase |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ACLY(ATP-citrate synthase) is also named as ACL. It is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA. ACLY serves as not only a target in oxygenated cells for suppression of lipid synthesis and histone acetylation, but also as a susceptible target in hypoxic cells to restore inhibition of glycolysis. In nonsmall cell lung carcinoma and hepatocellular carcinoma, ACLY is overexpressed compared with normal parenchyma suggesting that ACLY may represent a common target among highly malignant tumors(PMID:19795461). This protein has 2 isoforms produced by alternative splicing. This antibody is specific to ACLY. |
Immunogen | Immunogen: Recombinant protein of human ACLY Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [ATPCL; CLATP] |
Gene, Accession # | [ACL], Gene ID: 47, NCBI: NP_001087.2, UniProt: P53396 |
Catalog # | MBS8501078 |
Price | $310 |
Order / More Info | ATP-Citrate Lyase Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |