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Antigenic Specificity | RNF34 (C-term), 283-311 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, mouse, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This RNF34 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 283-311 amino acids from the C-terminal region of human RNF34. The protein encoded by this gene contains a RINF finger, amotif known to be involved in protein-protein and protein-DNAinteractions. This protein interacts with DNAJA3/hTid-1, which is aDnaJ protein reported to function as a modulator of apoptosis.Overexpression of this gene in Hela cells was shown to confer theresistance to TNF-alpha induced apoptosis, suggesting ananti-apoptotic function of this protein. This protein can becleaved by caspase-3 during the induction of apoptosis.Alternatively spliced transcript variants encoding distinctisof |
Immunogen | n/a |
Other Names | [E3 ubiquitin-protein ligase RNF34; 632- {ECO:0000269|PubMed:25012219; ECO:0000269|Ref13}; Caspase regulator CARP1; Caspases-8 and -10-associated RING finger protein 1; CARP-1; FYVE-RING finger protein Momo; RNF34 HGNC:17297)] |
Gene, Accession # | [RNF34], Gene ID: 80196, NCBI: NP_001243787.1, UniProt: Q969K3 |
Catalog # | MBS9203074 |
Price | $165, $370 |
Order / More Info | RNF34 (C-term), 283-311 Antibody from MYBIOSOURCE INC. |
Product Specific References | Erlbruch, A., et al. Proteomics 10(16):2890-2900(2010) Yang, W., et al. Cell Cycle 7(5):670-682(2008) Yang, W., et al. J. Biol. Chem. 282(5):3273-3281(2007) Konishi, T., et al. Mol. Cancer Ther. 4(5):743-750(2005) Sasaki, S., et al. J. Exp. Clin. Cancer Res. 23(3):507-512(2004) |