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Antigenic Specificity | Mouse CD206 |
Clone | [C068C2] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a |
Format | phycoerythrin (PE) conjugate |
Size | 20 tests, 50 tests, 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD206, also known as mannose receptor (MR), is a 175 kD type I membrane protein. It is a pattern recognition receptor (PRR) belonging to the C-type lectin superfamily. MR is expressed on macrophages, dendritic cells, Langerhans cells, and hepatic or lymphatic endothelial cells. MR recognizes a range of microbial carbohydrates bearing mannose, fucose, or N-acetyl glucosamine through its C-type lectin-like carbohydrate recognition domains, sulfated carbohydrate antigens through its cysteine-rich domain, and collagens through its fibronectin type II domain. MR mediates endocytosis and phagocytosis as well as activation of macrophages and antigen presentation. It plays an important role in host defense and provides a link between innate and ada |
Immunogen | n/a |
Other Names | [MMR; MR; MRC1; macrophage mannose receptor; mannose receptor] |
Gene, Accession # | [CD206], Gene ID: 17533, NCBI: NP_032651.2, UniProt: Q61830 |
Catalog # | MBS2556981 |
Price | $75, $90, $110 |
Order / More Info | Mouse CD206 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Wileman TE, et al. 1986. P. Natl. Acad. Sci. USA 83:2501. 2. Apostolopoulos V, et al. 2001. Curr. Mol. Med. 1:469. 3. Burgdorf S, et al. 2006. J. Immunol. 176:6770. 4. McKenzie EJ, et al. 2007. J. Immunol. 178:4975. |