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Antigenic Specificity | MEK 1/2 (pSER218/222) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | bovine (expected from sequence), chicken (expected from sequence), dog (expected from sequence), monkey (expected from sequence), mouse, rat (expected from sequence), Xenopus (expected from sequence), zebrafish (expected from sequence) |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB)* |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This item is specific for MEK 1 and MEK 2, (also known as MAP2K1 and MAP2K2 respectively), when phosphorylated at serine 218 and 222. . . MEK1 and 2 are related dual specificity protein kinases from the MAP kinase family. These proteins are activated by phosphoryation at serine 218 and 222, and play a critical role in mitogen growth factor signal transduction. MBS221794 is specific for MEK 1 and MEK 2, (also known as MAP2K1 and MAP2K2 respectively), when phosphorylated at serine 218 and 222. MEK1 and 2 are related dual specificity protein kinases from the MAP kinase family. These proteins are activated by phosphoryation at serine 218 and 222, and play a critical role in mitogen growth factor signal transduction. |
Immunogen | Immunogen: Synthetic phosphopeptide corresponding to an amino acid sequence which includes phosphorylated ser 218 and 222 within human MEK1 and 2. Buffer Solution: 10mM HEPES pH7.5 Antiserum Preparation: Antisera to phosphorylated MEK were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography. Target Species: Human |
Other Names | [dual specificity mitogen-activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 1; dual specificity mitogen-activated protein kinase kinase 1; ERK activator kinase 1; MAPK/ERK kinase 1; MAPKK 1; MEK 1; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); mitogen-activated protein kinase kinase 1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1], [MAP2K1; MAP2K1; CFC3; MEK1; MKK1; MAPKK1; PRKMK1; MEK1; PRKMK1; MAP kinase kinase 1; MAPKK 1; MKK1; MEK 1] |
Gene, Accession # | [MEK 1/2], Gene ID: 5604, NCBI: NP_002746.1 |
Catalog # | MBS221794 |
Price | $550 |
Order / More Info | MEK 1/2 (pSER218/222) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |