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Antigenic Specificity | Keratin 8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Keratin 8 antibody detects endogenous levels of total Keratin 8. Description: K8 a type II cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Phosphorylation of keratins at specific sites affects their organization, assembly dynamics, and their interaction with signaling molecules. Phsophorylated by p38 kinase, regulating cellular keratin filament reorganization.Function: Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.Subunit Structure: Heterotetramer of two type I and two type II keratins. KRT8 associates with KRT18. Asso |
Immunogen | Immunogen: A synthesized peptide derived from human Keratin 8 Subcellular Location: Cytoplasm. Nucleus, Nucleoplasm. Nucleus Matrix. Tissue Specificity: Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity. |
Other Names | [CARD2; CK 8; CK-8; CK8; CYK8; CYKER; Cytokeratin endo A; Cytokeratin-8; DreK8; EndoA; K2C8; K2C8_HUMAN; K8; Keratin 8; Keratin type II cytoskeletal 8; Keratin, type II cytoskeletal 8; Keratin-8; KO; Krt 2.8; KRT8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; Type-II keratin Kb8] |
Gene, Accession # | [KRT8], Gene ID: 3856, NCBI: NP_001243222.1, UniProt: P05787 |
Catalog # | MBS9600134 |
Price | $240, $280 |
Order / More Info | Keratin 8 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |