SRC8 (N-term), 9-38 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySRC8 (N-term), 9-38
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: chicken, mouse)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA), Immunohistochemistry (IHC)
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DescriptionThis SRC8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-38 amino acids from the N-terminal region of human SRC8. SRC8 is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This protein has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this protein contributes to tumor cell invasion and metastasis.
Immunogenn/a
Other Names[Src substrate cortactin; Amplaxin; Oncogene EMS1; CTTN; EMS1]
Gene, Accession #[CTTN], Gene ID: 2017, NCBI: NP_001171669.1, UniProt: Q14247
Catalog #MBS9202308
Price$165, $370
Order / More InfoSRC8 (N-term), 9-38 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesXu,X.Z., et.al, Mod. Pathol. 23 (2), 187-196 (2010) Saitoh,Y., et.al, Int. J. Oncol. 35 (6), 1277-1288 (2009)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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