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Antigenic Specificity | HP1 gamma Picoband |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Description: Chromobox protein homolog 3 is a protein that is encoded by the CBX3 gene in humans. At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but diff |
Immunogen | Immunogen: E Coli-derived human HP1 gamma recombinant protein (Position: A2-Q183). Subcellular Localization: Nucleus. Associates with euchromatin and is largely excluded from constitutive heterochromatin. May be associated with microtubules and mitotic poles during mitosis (Potential). |
Other Names | [Chromobox protein homolog 3; HECH; Heterochromatin protein 1 homolog gamma; HP1 gamma; Modifier 2 protein; CBX3] |
Gene, Accession # | [CBX3], Gene ID: 11335, NCBI: NP_009207.2, UniProt: Q13185 |
Catalog # | MBS1750581 |
Price | $315 |
Order / More Info | HP1 gamma Picoband Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |