IL10, 27-53 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityIL10, 27-53
Clone[530CT10.5.7]
Host SpeciesMouse
Reactive Specieshuman (predicted reactivity: EBV, monkey)
IsotypeIgM
Formatascites
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis IL10 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 27-53 amino acids from human IL10. The protein encoded by this gene is a cytokine producedprimarily by monocytes and to a lesser extent by lymphocytes. Thiscytokine has pleiotropic effects in immunoregulation andinflammation. It down-regulates the expression of Th1 cytokines,MHC class II Ags, and costimulatory molecules on macrophages. Italso enhances B cell survival, proliferation, and antibodyproduction. This cytokine can block NF-kappa B activity, and isinvolved in the regulation of the JAK-STAT signaling pathway.Knockout studies in mice suggested the function of this cytokine asan essential immunoregula
Immunogenn/a
Other Names[Interleukin-10; IL-10; Cytokine synthesis inhibitory factor; CSIF; IL10]
Gene, Accession #[IL10], Gene ID: 3586, NCBI: NP_000563.1, UniProt: P22301
Catalog #MBS9200076
Price$370
Order / More InfoIL10, 27-53 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesHuebinger, R.M., et al. J. Surg. Res. 164 (1), E141-E145 (2010) : Glocker, E.O., et al. Lancet 376 (9748), 1272 (2010) : Mosaad, Y.M., et al. Scand. J. Immunol. 72(4):358-364(2010) Kung, W.J., et al. Diabetes Technol. Ther. 12(10):809-813(2010) Santhosh, S., et al. Trop Gastroenterol 31(1):30-33(2010)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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