Edit |   |
---|---|
Antigenic Specificity | hnRPD (Phospho-Ser83) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of hnRPD only when phosphorylated at serine 83. Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Kajita Y., J. Biol. Chem. 270:22167-22175(1995).Dempsey L.A., Genomics 49:378-384(1 |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around phosphorylation site of Serine 83(N-S-S(p)-P-R) derived from Human hnRPD. |
Other Names | [ROD; AUF1; HNRPD] |
Gene, Accession # | [hnRPD], Gene ID: 3184, NCBI: NP_001003810.1, UniProt: Q14103 |
Catalog # | MBS9404676 |
Price | $200, $255 |
Order / More Info | hnRPD (Phospho-Ser83) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |