Edit |   |
---|---|
Antigenic Specificity | AMPK alpha (PRKAA1) (S487), 474-502 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.31 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This AMPK alpha(PRKAA1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-502 amino acids from human AMPK alpha(PRKAA1). PRKAA1 belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. |
Immunogen | n/a |
Other Names | [5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1; PRKAA1; AMPK1] |
Gene, Accession # | [PRKAA1], Gene ID: 5562, NCBI: NP_006242.5, UniProt: Q13131 |
Catalog # | MBS9209592 |
Price | $165, $370 |
Order / More Info | AMPK alpha (PRKAA1) (S487), 474-502 Antibody from MYBIOSOURCE INC. |
Product Specific References | Pang,T., J. Biol. Chem. 282 (1), 495-506 (2007) Crawford,R.M., Cell. Signal. 18 (10), 1595-1603 (2006) Crawford,R.M., Mol. Cell. Biol. 26 (15), 5921-5931 (2006) |