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Antigenic Specificity | COL17A1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous COL17A1 protein. COL17A1 (collagen type XVII alpha 1 chain) encodes the alpha chain of type XVII collagen. Unlike most collagens, collagen XVII is a transmembrane protein. Collagen XVII is a structural component of hemidesmosomes, multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane. Mutations in COL17A1 are associated with both generalized atrophic benign and junctional epidermolysis bullosa. Two homotrimeric forms of type XVII collagen exist. The full length form is the transmembrane protein. A soluble form, referred to as either ectodomain or LAD-1, is generated by proteolytic processing of the full length form. |
Immunogen | Immunogen: Synthetic peptide from human protein at AA range: 481-530 |
Other Names | [Rabbit COL17A1; COL17A1; BP180; BPAG2] |
Gene, Accession # | [COL17A1], Gene ID: 1308, NCBI: NP_000485.3, UniProt: Q9UMD9 |
Catalog # | MBS9708166 |
Price | $130, $220, $325 |
Order / More Info | COL17A1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |