Edit |   |
---|---|
Antigenic Specificity | Human Ephrin-B1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons. Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to |
Immunogen | Immunogen: Recombinant human Ephrin-B1 protein (28-237aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-20723 / sc-1011 / sc-910 |
Other Names | [EFL-3; ELK ligand; ELK-L; EPH-related receptor tyrosine kinase ligand 2; LERK-2; EFNB1; EFL3; EPLG2; LERK2], [EFNB1; EFNB1; CFND; CFNS; EFB1; EFL3; EPLG2; Elk-L; LERK2; EFL3; EPLG2; LERK2; ELK-L; LERK-2] |
Gene, Accession # | [EFNB1], Gene ID: 1947, NCBI: NP_004420.1, UniProt: P98172 |
Catalog # | MBS1493377 |
Price | $120, $160 |
Order / More Info | Human Ephrin-B1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |