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Antigenic Specificity | ELAVL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability (PubMed:14517288, PubMed:18285462). Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), stabilizing them, promoting ESCs differentiation. Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs (PubMed:8626503, PubMed:17632515, PubMed:18285462, PubMed:23519412). Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA, and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro (PubMed:8626503). Wit |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-326 of human ELAVL1 (NP 001410.2). |
Other Names | [HUR; Hua; MelG; ELAV1] |
Gene, Accession # | [ELAVL1], Gene ID: 1994, NCBI: Q15717.2, UniProt: Q15717 |
Catalog # | MBS8544476 |
Price | $280 |
Order / More Info | ELAVL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |