Erk1/2 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | Erk1/2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat, bovine, sheep, chicken, Fruit Fly, African Clawed frog |
| Isotype | n/a |
| Format | Peptide Affinity purified |
| Size | 0.025 mL |
| Concentration | 1 mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Detects ~44kda (ERK1) and ~42kDa (ERK2). The extracellular signal-regulated kinases 1 and 2 (ERK1 and ERK2), also called p44 and p42 MAP kinases, are members of the Mitogen Activated Protein Kinase (MAPK) family of proteins found in all eukaryotes. Because the 44 kDa ERK1 and the 42 kDa ERK2 are highly homologous and both function in the same protein kinase cascade, the two proteins are often referred to collectively as ERK1/2 or p44/p42 MAP kinase (1). They are both located in the cytosol and mitochondria (2). While the role of cytosol ERK1/2 is well studied and involved in multiple cellular functions (2), the role of mitochondrial ERK1/2 remains poorly understood. Both ERK 1 and 2 are activated by MEK1 or MEK2, by dual phosphorylation of |
| Immunogen | Immunogen: A 35 residue synthetic peptide, corresponding to Erk1 MAP kinase with the CGG spacer group added and the peptide coupled to KLH. Immunogen Species: Rat |
| Other Names | [Rabbit Rat Erk1/2; ERK1; ERK2; ERT1; ERT2; MAP kinase1; MAP kinase2; MAPK1; MAPK2; MAPK3; p38; p40; p41; p41mapk; p42 MAPK; p44 ERK1; p44 MAPK; PRKM1 PRKM2; PRKM3] |
| Gene, Accession # | [Erk1/2], Gene ID: 50689, NCBI: NP_059043.1, UniProt: P21708 |
| Catalog # | MBS8002000 |
| Price | $220 |
| Order / More Info | Erk1/2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Boulton TG. et al. (1991) Biochemistry. 30(1):278-86. 2. Yoon S., and Seger R. (2006) Growth Factors 24:21-44. 3. Wolf G. (2005) Antioxid Redox Signal 7:1337-1345. 4. Chuerland D., Marmor G., Shainskaya A. and Seger R. (2008) J Biol Chem. 5. Zhuang S., and Schnellmann R.G. (2006) J Pharmacol Exp Ther 319:991-997. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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