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Antigenic Specificity | SH2B3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of SH2B3 protein. SH2B3 (SH2B Adaptor Protein 3) encodes a member of the SH2B adaptor family of proteins, which are involved in a range of signaling activities by growth factor and cytokine receptors. The encoded protein is a key negative regulator of cytokine signaling and plays a critical role in hematopoiesis. Mutations in SH2B3 have been associated with susceptibility to celiac disease type 13 and susceptibility to insulin-dependent diabetes mellitus. Alternatively spliced transcript variants encoding different isoforms have been found for SH2B3. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human SH2B3 protein |
Other Names | [Rabbit SH2B3; SH2B adapter protein 3; Lymphocyte adapter protein; Lymphocyte-specific adapter protein Lnk; Signal transduction protein Lnk] |
Gene, Accession # | [SH2B3], Gene ID: 10019, NCBI: NP_001278353.1, UniProt: Q9UQQ2 |
Catalog # | MBS9710920 |
Price | $130, $220, $325 |
Order / More Info | SH2B3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |