Edit |   |
---|---|
Antigenic Specificity | NAIF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.02 mL, 0.06 mL, 0.12 mL |
Concentration | 1.5mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Human NAIF1 is located on chromosome 9q34. 11 and encodes 327 amino acids with a homeodomain-like region and two nuclear localization signals at its N-terminal region. NAIF1 is conserved across diverse species, including human, mouse, crab-eating macaque, dog, chicken and frog, and shares no obvious homology to any known genes or proteins. NAIF1 was predominantly localized in the nucleus. Overexpression of NAIF1 inhibited cell growth and induced apoptosis. Furthermore, NAIF1 transfection caused both decreases in mitochondrial membrane potential and caspase-3 activation. In summary, NAIF1 is a nuclear protein that induces apoptosis when overexpressed. |
Immunogen | Immunogen: Recombinant protein of human NAIF1 Calculated Molecular Weight: 35kDa |
Other Names | [C9orf90, bA379C10.2, RP11-379C10.2] |
Gene, Accession # | [NAIF1], Gene ID: 203245, NCBI: NP_931045.1 |
Catalog # | MBS2517177 |
Price | $110, $150, $225 |
Order / More Info | NAIF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |