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Antigenic Specificity | ESRP1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human ESRP1 (NP 060167.2). |
Other Names | [RBM35A; RMB35A; DFNB109] |
Gene, Accession # | [ESRP1], Gene ID: 54845, NCBI: NP_001030087, UniProt: Q6NXG1 |
Catalog # | MBS8549530 |
Price | $280 |
Order / More Info | ESRP1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |