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Antigenic Specificity | GSK-3alpha |
Clone | [1B10-G3-E9] |
Host Species | Mouse |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimers disease. [provided by RefSeq, Oct 2011]. UniPort Summary Function: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1. Requires primed phosphorylat |
Immunogen | Immunogen: Purified recombinant fragment of GSK3 alpha expressed in E Coli. Sequence Similarities: Contains 1 protein kinase domain. |
Other Names | [DKFZp686D0638; Glycogen synthase kinase 3 alpha; Glycogen synthase kinase-3 alpha; GSK 3 alpha; GSK 3A; GSK-3 alpha; Gsk3a; GSK3A_HUMAN; GSK3alpha; Serine/threonine protein kinase GSK3A], [GSK3A; DKFZp686D0638; GSK3A] |
Gene, Accession # | [GSK-3alpha], Gene ID: 2931, NCBI: NP_063937.2, UniProt: P49840 |
Catalog # | MBS475707 |
Price | $335 |
Order / More Info | GSK-3alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |