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Antigenic Specificity | GSAP - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, horse, human, rabbit, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against GSAP. It was validated on Western BlotTarget Description: Accumulation of neurotoxic amyloid-beta is a major hallmark of Alzheimer disease. Formation of amyloid-beta is catalyzed by gamma-secretase, a protease with numerous substrates. PION, or GSAP, selectively increases amyloid-beta production through a mechanism involving its interaction with both gamma-secretase and its substrate, the amyloid-beta precursor protein C-terminal fragment (APP-CTF). |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GSAP |
Other Names | [gamma-secretase-activating protein isoform a; Gamma-secretase-activating protein; gamma-secretase-activating protein; gamma-secretase activating protein; Protein pigeon homologGamma-secretase-activating protein 16 kDa C-terminal form; GSAP-16K] |
Gene, Accession # | [GSAP], Gene ID: 54103, NCBI: NP_059135, UniProt: A4D1B5 |
Catalog # | MBS3209173 |
Price | $335 |
Order / More Info | GSAP - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |