Human PTP1B Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Human PTP1B antibody, protein, ELISA kits.
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| Antigenic Specificity | Human PTP1B |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | DyLight 488 conjugate |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: No cross reactivity with other proteins. Tyrosine-protein phosphatase non-receptor type 1, also known as protein-tyrosine phosphatase 1B (PTP1B), is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative reg |
| Immunogen | Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human PTP1B (4-30aa EKEFEQIDKSGSWAAIYQDIRHEASDF), different from the related mouse sequence by three amino acids, and from the related rat sequence by two amino acids. |
| Other Names | [Rabbit IgG Human PTP1B DyLight 488 Conjugated, Flow Validated; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B; PTPN1; PTP1B; Protein tyrosine phosphatase, non-receptor type 1] |
| Gene, Accession # | [PTP1B], Gene ID: 5770, NCBI: NP_001265547.1, UniProt: P18031 |
| Catalog # | MBS1751258 |
| Price | $330 |
| Order / More Info | Human PTP1B Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Brown-Shimer S, Johnson KA, Lawrence JB, Johnson C, Bruskin A, Green NR, Hill DE (Aug 1990). Molecular cloning and chromosome mapping of the human gene encoding protein phosphotyrosyl phosphatase 1B. ProcNatlAcadSci USA. 87 (13): 5148-52. 2. Combs AP (March 2010). Recent advances in the discovery of competitive protein tyrosine phosphatase 1B inhibitors for the treatment of diabetes, obesity, and cancer. J. Med. Chem. 53 (6): 2333-44. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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