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Antigenic Specificity | Complement C3 (beta chain) |
Clone | polyclonal |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to Complement C3(beta chain). Human Complement C3 (C3) is synthesized as a single-chain pro-molecule (185 kDa) that tsuffers several posttranslational modifications. Before being a mature protein, C3 is split into beta-chain (70 kDa) and alpha chain (115 kDa) and forms a rare internal thioester bond. C3 plays a central role in the activation of the complement system. It's processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. |
Immunogen | n/a |
Other Names | [complement C3 preproprotein; Complement C3; complement C3; complement C3; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1], [C3; C3; ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p; CPAMD1; C3bc; ASP] |
Gene, Accession # | Gene ID: 718, NCBI: NP_000055.2, UniProt: P01024 |
Catalog # | MBS856767 |
Price | $280 |
Order / More Info | Complement C3 (beta chain) Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.Zhang H., Li X.-J., Martin D.B., Aebersold R.Nat. Biotechnol. 21: 660-666(2003). 2. Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.Bunkenborg J., Pilch B.J., Podtelejnikov A.V., Wisniewski J.R.Proteomics 4:454-465(2004). |