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Antigenic Specificity | IL2 (Center), 50-77 |
Clone | [627CT14.8.1] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ascites |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This IL2 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 50-77 amino acids from the Central region of human IL2. The protein encoded by this gene is a secreted cytokinethat is important for the proliferation of T and B lymphocytes. Thereceptor of this cytokine is a heterotrimeric protein complex whosegamma chain is also shared by interleukin 4 (IL4) and interleukin 7(IL7). The expression of this gene in mature thymocytes ismonoallelic, which represents an unusual regulatory mode forcontrolling the precise expression of a single gene. The targeteddisruption of a similar gene in mice leads to ulcerativecolitis-like disease, which suggests an essential role of this gene< |
Immunogen | n/a |
Other Names | [Interleukin-2; IL-2; T-cell growth factor; TCGF; Aldesleukin; IL2] |
Gene, Accession # | [IL2], Gene ID: 3558, NCBI: NP_000577.2, UniProt: P60568 |
Catalog # | MBS9200668 |
Price | $370 |
Order / More Info | IL2 (Center), 50-77 Antibody from MYBIOSOURCE INC. |
Product Specific References | Zhu, P., et al. J. Immunol. 185(9):5140-5149(2010) Muller, T., et al. Scand. J. Immunol. 72(4):365-371(2010) Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) : Horowitz, A., et al. J. Immunol. 185(5):2808-2818(2010) Wu, Z., et al. J Mol Cell Biol 2(4):217-222(2010) |