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Antigenic Specificity | GRM3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: GRM3 antibody detects endogenous levels of total GRM3. Description: L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III include |
Immunogen | Immunogen: A synthesized peptide derived from human GRM3 Subcellular Location: Cell Membrane Tissue Specificity: Detected in brain cortex, thalamus, subthalamic nucleus, substantia nigra, hypothalamus, hippocampus, corpus callosum, caudate nucleus and amygdala. |
Other Names | [GLUR3; Glutamate metabotropic receptor 3; Glutamate receptor metabotropic 3; GPRC1C; GRM3; GRM3_HUMAN; Metabotropic glutamate receptor 3; MGlu3; mGluR3] |
Gene, Accession # | [GRM3], Gene ID: 2913, NCBI: NP_000831.2, UniProt: Q14832 |
Catalog # | MBS9607648 |
Price | $240, $280 |
Order / More Info | GRM3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |