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Antigenic Specificity | Dok-5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Dok-5 Polyclonal Antibody detects endogenous levels of Dok-5 protein. The protein encoded by DOK5 (docking protein 5) is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. Unlike other DOK family proteins, this protein does not interact with RASGAP. This protein is up-regulated in patients with systemic sclerosis and is associated with fibrosis induced by insulin-like growth factor binding protein 5. Alternative splicing of DOK5 results in multiple transcript variants. |
Immunogen | Immunogen: Synthesized peptide derived from the internal region of human Dok-5 at AA range: 70-150 |
Other Names | [Rabbit Dok-5; DOK5; C20orf180; Docking protein 5; Downstream of tyrosine kinase 5; Insulin receptor substrate 6; IRS-6; IRS6] |
Gene, Accession # | [DOK-5], Gene ID: 55816, NCBI: NP_060901.2, UniProt: Q9P104 |
Catalog # | MBS9706413 |
Price | $130, $220, $325 |
Order / More Info | Dok-5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |