Human CD252(OX40L) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CD252(OX40L) |
| Clone | [ANC10G1] |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1k |
| Format | phycoerythrin (RPE) conjugate |
| Size | 120 tests |
| Concentration | Volume: 0.2ml |
| Applications | Flow Cytometry (FC/FACS), ELISA (EIA), Blocking |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Information: Human CD252 (CD134L, OX-40L) is a type II membrane protein with homology to TNF which is expressed on activated B cells and activated endothelial cells. CD252 binds to CD134 present on activated T cells, providing a costimulatory signal (1). This pathway seems to be more effective for costimulation of CD4 helper T cells than for CD8 effector T cells (4). Blockade of this interaction in mouse abrogated immunological effects in several models of inflammation and rejection (5,6,7,8). Antibody from clone ANC10G1 binds to CD252 on the cell surface of HUVEC in Flow cytometry, and blocks binding of recombinant CD134-muIg. |
| Immunogen | Immunogen: Human HUVEC and Recombinant soluble human CD252 |
| Other Names | n/a |
| Gene, Accession # | [CD252] |
| Catalog # | MBS666102 |
| Price | $470 |
| Order / More Info | Human CD252(OX40L) Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1) W. R. Godfrey, et al, (1994) J Exp Med 180: 757-763. 2) L.M. Higgins, et al, (1999) J Immunol 162: 486-493. 3) A.D. Weinberg, et al, (1999) J Immunol 162: 1818-1826. 4) V.Y. Taraban, et al, (2002) Eur J. Immunol. 32: 3617-3627. 5) V. Malmstrom, et al, (2001) J Immunol 166: 6972. 6) C. Nohara, et al, (2001) J Immunol 166: 2108-2115. 7) X. Yuan, et al, (2003) J Immunol 170: 2949-2955. 8) L. Tian, et al, (2002) Transplantation 74(1): 133-138. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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