SH3BP2 (Center), 151-180 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SH3BP2 (Center), 151-180 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.3 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This SH3BP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the Central region of human SH3BP2. The protein encoded by this gene has an N-terminalpleckstrin homology (PH) domain, an SH3-binding proline-richregion, and a C-terminal SH2 domain. The protein binds to the SH3domains of several proteins including the ABL1 and SYK proteintyrosine kinases, and functions as a cytoplasmic adaptor proteinto positively regulate transcriptional activity in T, naturalkiller (NK), and basophilic cells. Mutations in this gene result incherubism. Multiple transcript variants encoding different isoformshave been found for this gene. |
| Immunogen | n/a |
| Other Names | [SH3 domain-binding protein 2; 3BP-2; SH3BP2; 3BP2] |
| Gene, Accession # | [SH3BP2], Gene ID: 6452, NCBI: NP_001116153.1, UniProt: P78314 |
| Catalog # | MBS9203862 |
| Price | $165, $370 |
| Order / More Info | SH3BP2 (Center), 151-180 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Lietman, S.A., et al. J. Orthop. Res. 28(11):1425-1430(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Davila, S., et al. Genes Immun. 11(3):232-238(2010) Amaral, F.R., et al. J. Oral Pathol. Med. 39(3):269-274(2010) Shukla, U., et al. J. Biol. Chem. 284(49):33719-33728(2009) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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