SFRS7 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySFRS7
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatimmunogen affinity purified
Size0.05 mL, 0.1 mL
Concentration1.0 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThe antibody detects endogenous levels of total SFRS7 protein. Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.Cavaloc Y., EMBO J. 13:2639-2649(1994).Popielarz M., J. Biol. Chem. 270:17830-17835(1995).The MGC Project Team, Genome Res. 14:2121-2127(2004).
ImmunogenImmunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human SFRS7.
Other Names[SFR7; Splicing factor 9G8; Splicing factor; arginine/serine-rich 7]
Gene, Accession #[SFRS7], Gene ID: 6432, NCBI: NP_001026854.1, UniProt: Q16629
Catalog #MBS9404515
Price$200, $255
Order / More InfoSFRS7 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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