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Antigenic Specificity | SFRS7 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total SFRS7 protein. Required for pre-mRNA splicing. Can also modulate alternative splicing in vitro. Represses the splicing of MAPT/Tau exon 10. May function as export adapter involved in mRNA nuclear export such as of histone H2A. Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway); enhances NXF1-NXT1 RNA-binding activity. RNA-binding is semi-sequence specific.Cavaloc Y., EMBO J. 13:2639-2649(1994).Popielarz M., J. Biol. Chem. 270:17830-17835(1995).The MGC Project Team, Genome Res. 14:2121-2127(2004). |
Immunogen | Immunogen Type: Peptide Immunogen Description: Synthesized peptide derived from internal of human SFRS7. |
Other Names | [SFR7; Splicing factor 9G8; Splicing factor; arginine/serine-rich 7] |
Gene, Accession # | [SFRS7], Gene ID: 6432, NCBI: NP_001026854.1, UniProt: Q16629 |
Catalog # | MBS9404515 |
Price | $200, $255 |
Order / More Info | SFRS7 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |