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Antigenic Specificity | DAP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/mL |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: DAP antibody is human, mouse and rat reactive. DAP Antibody: The Death-associated protein (DAP) is a basic proline-rich 15kDa protein that as a positive mediator of programmed cell death that is induced by interferon-gamma (1). DAP is also a direct substrate of mammalian target of rapamycin (mTOR), a serine/threonine kinase that regulates cell growth and cell cycle, and a negative regulator of autophagy. Under rich nutrient conditions, mTOR phosphorylates DAP at Ser3 and Ser51; under starvation conditions, these residues are dephosphorylated and DAP is converted into an active suppressor of autophagy (2). |
Immunogen | Immunogen: DAP antibody was raised against a 19 amino acid peptide near the carboxy terminus of human DAP. Buffer: DAP Antibody is supplied in PBS containing 0.02% sodium azide. |
Other Names | [DAP; DAP1; Death-associated protein 1; DAP-1; death-associated protein], [DAP; DAP; DAP1; DAP-1] |
Gene, Accession # | [DAP], Gene ID: 1611, NCBI: NP_004385, UniProt: P51397 |
Catalog # | MBS153339 |
Price | $375 |
Order / More Info | DAP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |