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Antigenic Specificity | HSP60 |
Clone | [LK1] |
Host Species | Mouse |
Reactive Species | human, mouse, rat, bovine, dog, chicken, Fruit Fly, guinea pig, hamster, monkey, porcine, rabbit, sheep, African Clawed frog, plant, Soybean, silkworm |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA (EIA), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Detects ~60kDa. In both prokaryotic and eukaryotic cells, the misfolding and aggregation of proteins during biogenesis and under conditions of cellular stress are prevented by molecular chaperones. Members of the HSP60 family of heat shock proteins are some of the best characterized chaperones. HSP60, also known as Cpn60 or GroEl, is an abundant protein synthesized constitutively in the cell that is induced to a higher concentration after brief cell shock. It is present in many species and exhibits a remarkable sequence homology among various counterparts in bacteria, plants, and mammals with more than half of the residues identical between bacterial and mammalian HSP60 (1-3). Whereas mammalian HSP60 is localized within the mitochondria, pl |
Immunogen | Immunogen: Recombinant human HSP60 Immunogen Species: Human |
Other Names | [Mouse Human HSP60 IgG1; HSP60, Clone LK1; CPN60; GROEL; HLD4; HSP 60; HSP65; HSPD1; HuCHA60; SPG 13] |
Gene, Accession # | [HSP60], Gene ID: 3329, NCBI: NP_002147.2, UniProt: P10809 |
Catalog # | MBS8001867 |
Price | $215 |
Order / More Info | HSP60 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Hartl, F.U. (1996) Nature 381: 571-579. 2. Bukau, B. and Horwich, A.L. (1998) Cell 92: 351-366. 3. Hartl, F.U. and Hayer-Hartl, M. (2002) Science 295: 1852-1858. 4. Jindal, S., et al. (1989) Molecular and Cellular Biology 9: 2279-2283. 5. La Verda, D., et al (1999) Infect Dis. Obstet. Gynecol. 7: 64-71. 6. Itoh, H. et al. (2002) Eur. J. Biochem. 269: 5931-5938. 7. Gupta, S. and Knowlton, A.A. J. Cell Mol Med. 9: 51-58. 8. Deocaris, C.C. et al. (2006) Cell Stress Chaperones 11: 116-128. 9. Lai, H.C. et al. (2007) Am. J. Physiol. Endocrinol. Metab. 292: E292-E297. 10. Gao, Y.L., et al (1995) J. of Immunology 154: 3548-3556. 11. Neuer, A., et al (1997) European Society for Human Reproduction and Embryology 12(5):925-929. 12. Bason, C., et al (2003) Lancet 362(9400): 1971-1977. |