TYK2 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | TYK2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Tyk2, a member of the Jak family of protein tyrosine kinases, associates with and is activated by receptors for many cytokines including IL-13, the IL-6 family, IL-10, and interferon-alpha and beta (1-3). Following ligand binding, Tyk2 is activated by phosphorylation on Tyr1054 and/or Tyr1055 (4). Tyk2 is required for the tyrosine phosphorylation of Stat3 in the IFN-beta signaling cascade (5). |
| Immunogen | Immunogen: Recombinant protein of human TYK2 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [JTK1] |
| Gene, Accession # | [TYK2], Gene ID: 7297, NCBI: NP_003322.3, UniProt: P29597 |
| Catalog # | MBS8501416 |
| Price | $310 |
| Order / More Info | TYK2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Velazquez, L. et al. (1995) J. Biol. Chem. 270, 3327-3334. 2. Stahl, N. et al. (1994) Science 263, 92-95. 3. Leonard, W.J. (1998) Annu. Rev. Immunol. 16, 293-322. 4. Grauzzi, M.C. et al. (1996) J. Biol. Chem. 271, 20494-20500. 5. Rani, M.R. et al. (1999) J. Biol. Chem. 274, 32507-32511. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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